Name | glucose dehydrogenase |
Synonyms | EC 1.1.1.47 glucose dehydrogenase |
CAS | 9028-53-9 |
EINECS | 232-836-9 |
Appearance | Form powder, color white |
Storage Condition | -20°C |
MDL | MFCD00131181 |
Physical and Chemical Properties | EPA Chemical Information Dehydrogenase, glucose (9028-53-9) |
Use | Application of glucose dehydrogenase can be widely used in the oxidative decomposition of glucose molecules to generate gluconic acid; it reacts with oxidized coenzyme NAD or NADP to generate reduced coenzyme NADH or NADPH; it acts with ketone reductase and coenzyme The specific carbonyl compounds produce chiral alcohols with high optical purity. |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
WGK Germany | 3 |
FLUKA BRAND F CODES | 10-21 |
HS Code | 35079090 |
Reference Show more | 1. [IF = 10.618] Tao Chen et al."A signal amplification system constructed by bi-enzymes and bi-nanospheres for sensitive detection of norephine and miRNA." Biosens Bioelectron. Please note: for some products, our company can only provide some information. We do not guarantee the authority of the information provided, and only provide reference and research for customers. storage conditions: -20 °c Thermal stability: < 50 °c (pH 8.0, 30min) pH Stability: 6.0-9.0 (25 °c, 24hr) optimal temperature: 55 ℃ optimal pH: 9.0 Michaelis constant: 9.2 × 10 μm (D-Glucose );8.6 × 10 μm (NAD ) Isoelectric point: 6.5 Molecular weight: 29KD (SDS-PAGE) |
introduction
glucose dehydrogenase is a white amorphous powder. α-galactosidase catalyzes the hydrolysis of α-galactosidine bond, which can transform and decompose the anti-nutritional factor α-galactosidine in feed and soybean food to improve its nutritional composition. In addition, the enzyme has certain applications in pharmaceutical, thickener treatment and paper industry.
mechanism of action
Glucose dehydrogenase is through the pentose phosphate pathway, which specifically oxidizes and decomposes glucose molecules to generate gluconic acid, which is accompanied by the production of hydrogen anions. The role of this enzyme also requires the participation of oxidized coenzyme NAD or NADP. The electron acceptor NAD or NADP quickly binds to the generated hydrogen anion to generate reduced coenzyme NADH or NADPH, forming a cofactor regeneration cycle.